Spring Office Hours:

Monday 9:00a - 12:00p, 1:00p - 5:00p Tuesday 1:00p - 5:00p
Wednesday 9:00a 12:00p, 1:00p - 5:00p Thursday 1:00p 2:30p
Friday 9:00a - 12:00p, 1:00p - 3:00p
Topic:
VIRUSES: REFORMING THE KILLERS
I will open with discussion of what viruses are and how they cause disease, then go to how they have been used to treat disease, (vaccines, genetic engineering), considering not only the value of their use but also the risks.

References for your reading:

1.Glass, R. I., J. Gentsch, and J. C. Smith. 1994. Rotavirus

vaccines:success by reassortment? Science, 265: 1389-1390. (assigning entire article)

2.Pelczar, M. J., Jr., E. C. S. Chan, and N. R. Krieg. 1993.

Microbiology:concepts and applications. McGraw-Hill, New York. (assigning section on "Benefits and potential hazards of genetic engineering: (including a box "Engineering a vaccine against hepatitis type B" pp. 392-395)

3.Rabinowitch, N. R., P. McInnes, D. L. Klein, and B. F. Hall.

1994. Vaccine technologies: view to the future. Science, 265: 1401-1404. (assigning only the part on vaccine vectors, and the conclusion)

4.Stringfellow, D. A. 1988. Viral pathogenesis and host resistance to infection. In Stringfellow, D. A., Editor, Virology, A Scope Publication, Chapter 4. Upjohn, Kalamazoo, (assigning entire chapter)

5.Tizard, I. R. 1995. Immunology: an introduction, 4th edition. Saunders, Philadelphia. (assigning sections on "Adverse consequences of vaccination" and "Benefits of vaccination" from chapter on vaccines)

6.Varmus, H. 1988. Retroviruses. Science, 240: 1427-1435. (assigning sections on "Retroviruses as Pathogens in Humans and Animals" and "Retroviruses as tools for Studying Development, Delivering Genes, and Curing Diseases")